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Disksintegrated Hardware, utility and Virtualization solution to provide institution of Pittsburgh With improved can charge mark downs and a new business Storage Infrastructure
ARMONK, ny - 12 Sep 2007: IBM (NYSE: IBM) today announced that it has shipped the 25,000th excessive-conclusion disk storage answer to the institution of Pittsburgh. the brand new disk storage answer is a component of a hardware, application and virtualization storage infrastructure to increase the researching atmosphere for faculty and team of workers, permit the school to reduce its complete can charge of ownership, enhance information middle power effectivity and reply hastily to storage infrastructure calls for.
The university of Pittsburgh has more than 33,000 full- and part-time college students along with more than 12,000 faculty and group of workers at its 5 western Pennsylvania campuses. during the past, the know-how wants of the college -- pupil statistics, e mail, archives, school statistics, worker assistance and mission essential functions -- resided on disparate storage solutions that were expanding past the skill of the existing infrastructure. the brand new infrastructure helps help the studying process through making the entry to suggestions quicker, richer, extra inclusive and significantly engaging.
The school needed to create an commercial enterprise storage solution that would provide it three key benefits:
a new storage infrastructure with the capacity to grow with the school of Pittsburgh as necessary;
improved equipment reliability with decreased downtime, and availability 24/7/365; andA tremendously extra manageable storage solution that might reduce fees and supply improved gadget efficiency via virtualization.
"The university of Pittsburgh helps big enterprise methods, and the quantity and complexity of new methods continue to develop. To without problems manage these methods it was crucial to establish an commercial enterprise storage solution that might leverage our latest investments in storage, make allocation of storage bendy and conscious of undertaking wants, give centralized administration, and present the reliability and balance we require. The integrated IBM storage solution met these necessities," said Jinx Walton, Director of Computing features and programs development on the tuition of Pittsburgh.
The university of Pittsburgh's total solution will consist of the IBM SAN volume Controller storage virtualization answer spread throughout two IBM gadget Storage DS8300 techniques applying CISCO SAN switches, which may be used for Tier 1 and Tier 2 storage needs. An IBM equipment Storage DS4800 should be used for Tier 3 and back-up, whereas IBM Tivoli productivity core (TPC) will manipulate the whole ambiance. greater than 325 terabytes of information can be stored on the new infrastructure -- the equal of storing greater than 162 billion pages of text.
These high-end DS8000 hardware disk storage methods are the 25,000th programs shipped from IBM's factories, courting back eight years to when the first enterprise Storage gadget turned into shipped in 1999.
"For the first time, IBM's education specialists and the school of Pittsburgh are working together and making a highly integrated storage answer with a view to aid its college students, staff, and faculty entry assistance immediately," spoke of Barry Rudolph, vice chairman, IBM gadget Storage. "or not it's a milestone in the heritage of the IBM agency to attain 25,000 high-end disk storage solutions shipped, and definitely indicates that our purchasers continue to demand IBM for their storage needs. Our goal right here is to deliver a storage infrastructure that can be official, cost productive, and respond hastily to the college of Pittsburgh's needs and reserve it time, substances, power and cash."
IBM global technology features may be featuring over 300 hours of protection, implementation, and practising features, and IBM world Financing leasing could be used to comprehensive the deal. financial terms of the deal aren't being disclosed.
in keeping with IDC, IBM changed into the number 1 employer of storage hardware from a mixed worldwide profits disk and tape point of view in 2006 (1). the new institution of Pittsburgh storage answer is changing an existing non-IBM storage solution and is slated to head live this yr.
For greater assistance about IBM gadget Storage solutions, please discuss with: www.ibm.com/storage
For greater counsel concerning the university of Pittsburgh, please talk over with: www.pitt.edu
Contact(s) informationCharles ZinkowskiIBM global Media Relations917email@example.com Thomas business replace
The partnership is expected to aid Suzlon expand its presence globally via bringing extra efficiency to its global operations and adorning productiveness of IT functions, IBM referred to in a statement.
youngsters the company didn't disclose the deal dimension of the contract.
"we've prolonged our relationship with IBM right into a full-fledged strategic partnership, for its capability to deliver differentiated services and bring tangible effects," Suzlon energy President, assistance know-how, Shirish Godbole observed.
IBM will aid Suzlon optimise its expenses and resources and allow the enterprise's IT crew to focus more on the transformational capabilities of IT and stream past familiar transaction management.
"we're excited with the Suzlon engagement and believe this as a good possibility to work with a consumer who is in the business of generating eco-friendly power," IBM India/South Asia international company services Managing accomplice Vanitha Narayanan mentioned.
IBM will also support Suzlon streamline its IT operations and increase the degrees of serviceability to enterprise. throughout this engagement, IBM will deliver Suzlon with full-scope software management service, along with seamless IT support for its operations globally.
Suzlon also these days upgraded its storage infrastructure with IBM's subsequent technology, high conclusion open disk storage device.
Suzlon has element-selected and built-in manufacturing gadgets across the world and analysis and construction (R&D) centres in India, Belgium, Denmark, Germany and The Netherlands.
Shares of Suzlon were trading at Rs 58 on the BSE, down by using 1.19 per cent from the previous close.
In 1985, Core international developed its business by using trashing IBM disk drives in a notorious ad campaign.
The Boca Raton business offered $1,000 rebates to homeowners of IBM`s AT computer systems who had been willing to change in their disk drives for those engineered by way of Core. In a biting advert crusade, Core proclaimed, ``We`re gonna deep-six thousands of them as a result of that`s the place they belong.``
these days, Core has long past from an IBM basher to an IBM booster. The company is working complicated to make sure its high-efficiency disk drives, which might be used to shop giant quantities of statistics, run on IBM`s true own computer systems.
``We recognized appropriate away that we had to get on board or fall at the back of,`` said John Simonds, Core`s advertising director. ``For us to reside in business, we must guide IBM. No count number what americans say, IBM is no. 1.``
ultimate spring, Core was one among most effective 5 organisations making particular enlargement boards, referred to as ``busmasters,`` that assist to completely make the most the brand new Micro Channel design used in excessive-end PS/2 machines. geared up with its own microprocessor, Core`s busmasters can retrieve facts kept in disk drives directly devoid of burdening the PS/2`s central processor. That permits the laptop to devote all its vigour to working application in preference to diverting vigor to operate disk drives.
And, an upgraded busmaster that Core plans to ship in the 2d quarter of this 12 months could play a crucial position in assisting IBM win again market share within the local area community, or LAN, market.
LANs link very own computer systems, minicomputers and even mainframe computer systems into a single network.
they're probably the most widespread computer trends of late as a result of they enable employees to share data on the identical desktop device.
Core`s new busmaster controller will enhance the quantity of memory of IBM personal computer systems fivefold and reduce the time essential to entry facts by using up to 20 times, Core President Hal Prewitt said.
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Sony is rolling out an A4-sized digital paper device it has been constructing for a long time now. The device combining eReader and pill points could be launched in Japan and will promote for a gorgeous cumbersome rate.
This ordinary hybrid elements an superb 13.3-inch touchscreen E-ink display, whatever thing that’s no longer very common on the market these days. It points a 1200 x 1600 pixel resolution and is Wi-Fi-enabled.
Sony has developed this device specially for highly specialized agencies and is attaching a hefty expense tag too, of about JPY100,000 / $1,000 / $746. It’s basically more expensive than the iPad Air, however the Apple slate covers the familiar purchaser base, generally.
The product became developed in order to motivate americans working in workplaces to change copying and handwriting on paper with digital options. therefore, images and text are naturally displayed because of the sixteen tiers of grey scale.
Sony claims that the E-Ink Mobius screen will enable clients to write down more comfortably on the machine, when in comparison to different tablet-stylus combos available.
The absence of a “touch panel” and glass layers additionally gives the look that one is writing without delay on the gadget. The “E Ink Mobius” is able to running up to three weeks on a full can charge.
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Our analyze demonstrates the efficacy of autologous PRGD in patients unresponsive to prior cures, with first rate results on all GVHD-related ocular effects. At 30 days, round 80% of patients responded, although that many had extreme DES. Of notice, our definition of response become very conservative (development in all symptoms and as a minimum one sign). Response turned into additionally maintained at 6 months.
All GVHD-linked ocular symptoms enhanced in most sufferers, above all photophobia, which is one of those that have an impact on heavily on sufferers’ nice of life and each day activities.
Tear damage up time enhanced in all responders and turned into linked to a variable growth of all different indications; really, the growth of the anterior section floor is accompanied with the aid of a reduction of fluorescein staining (expression of corneal epithelium loss) and conjunctival lissamine staining (that assesses lifeless conjunctival cells). The reduced corneal harm determines an improved and prolonged tear movie balance.
curiously, premiere-corrected visible acuity did not enormously enrich; in reality, decline in visual acuity is doubtless regarding other motives (for example, conditioning regimen and steroids) that assess cataract onset. also, Schirmer’s check did not trade vastly, as a result of PRGD remedy cannot cut back the damage caused through fibroblastic and lymphocytic infiltrates in the lacrimal glands. besides the fact that children, Schirmer’s look at various should be assessed on the time of medicine to accurately examine the disease stage.
however that the majority responders didn't gain comprehensive normalization of signs and signals, the improvement acquired become sufficiently marked as to give enormous amelioration of sufferers’ pleasant of lifestyles and return to way of life activities, in certain reading, driving and computing device utilization.
We suggest that ophthalmological contrast becomes part of the ordinary monitoring of cGVHD patients, to right away identify patients with oGVHD at an early stage; this should still on the spot timely medicine of ocular lesions, to evade the irreversible complications that deeply compromise visual acuity and first-rate of lifestyles, and for which no helpful treatment exists.2, three, 5, eight In particular, in our opinion, if DES grade is 1, sufferers may still be treated with preservative-free artificial tears, if DES is >1, patients can endure PRGD therapy, to be maintained future if responders.
youngsters, we additionally propose that PRGD may still not be used for huge ulcers where neovascularization (herbal repairing mechanism of corneal stroma) has already happened, because PDGFs may additional raise the formation of latest vessels and subsequent corneal opacity, rushing up visible loss.29, 30
PDGF-AB, EGF, vascular endothelial increase aspect, insulin-like increase ingredient 1 and transforming boom aspect-β1 are concerned within the community of proliferation, differentiation, migration and apoptosis of corneal cells contributing to epithelial renewal.31, 32, 33
there is in vitro proof that PRG is richer in PDGF-AB, EGF and transforming boom aspect-β1 than serum and improved stimulates boom of corneal epithelial cells.22 This encouraged the use of PRGs for treating DES, corneal lesions, neurotrophic keratitis and persistent corneal epithelial defects with promising consequences.22, 34, 35, 36, 37 in reality, PRG has lately been proven to be positive in a variety of autoimmune ailments involving the attention and causing DES.38
The prompt corneal re-epithelization brought on by the cooperation of PDGFs (corresponding to EGF, PDGFA-B, promoting in selected cell proliferation) and the inhibitors of inflammation (for instance, IL-1 receptor antagonist and inhibitors of metalloproteinases)18, 22 can also clarify the brilliant consequences we got as early as at 30 days of treatment additionally in this complicated set of sufferers. Response turned into additionally accompanied in patients with very severe corneal harm and in those with longer historical past of oGVHD. interestingly, seven of our patients had no longer in the past answered to autologous serum however answered to PRGD, this can be defined through the higher awareness of PDGFs in PRGD than in serum.22
We didn't find an affiliation between PDGFs concentration or variety of platelets in peripheral blood and response. The high interpatient variability in particular person PDGFs may also explain this finding, as our look at changed into insufficiently powered to realize this impact.39 As all patients had a comparatively high and homogeneous variety of platelets in peripheral blood, we are able to postulate that PDGFs steadiness in PRGD became excessive enough to set off corneal restoration in all patients, even if the minimal attention of PDGFs sufficient to set off the healing technique is not general.
We organized PRGD the usage of autologous platelet-prosperous plasma after freezing thawing at a closing dilution of 30percent20 rather than with a chemical mechanism as used with the aid of others,38 to stay away from the chance of sensitization and consequent terrible tolerability.5 in keeping with the high concentration of PDGFs in PRGD, we also determined to in the reduction of the frequency of instillation to four instances a day to ensure improved affected person compliance. For assessment, serum has been always administered 10 times a day.15
the use of autologous PRGD prevented the risk of infections regarding using homologous blood. Importantly, we had to accept as true with the heavy immunosuppressive repute of our sufferers and the problem for infection and an infection perhaps associated with use of a single vial for a couple of times.5 We therefore prepared small aliquots of PRGD for use for a maximum of 24 h at four °C and urged patients to an accurate manipulation. definitely we did not study any conjunctivitis regarding PRGD infection.
To our competencies, this is the first look at the use of platelet lysate within the field of oGVHD; its strengths are that the affected person population changed into represented by patients unresponsive to different remedies, and therefore it might prove much more valuable as a primary-line remedy; 2nd, we used a brand new methodology for instruction and storage, to overcome the drawbacks of outdated therapeutic makes an attempt with serum; finally, a single ophthalmologist performed all clinical assessments, for this reason it's unlikely that alterations in clinical parameters are as a result of distinct interpretations.
youngsters, a number of important limitations want highlighting. First, the restricted pattern doesn't enable extra in-depth analyses on elements favoring response. really, despite its have an effect on on best of life, oGVHD is commonly clinically considered a ‘2d-expense’ manifestation of cGVHD, and few patients are observed the ophthalmologist, often late at some point of disorder.
moreover, the clinician become now not blind to the treatment. also, there changed into no control neighborhood since the circumstance of the ocular floor can deteriorate unexpectedly in patients with cGVHD, and it may well be problematic to select manage topics to be handled with standard artificial eye drops, as stated via others.15
in addition, comply with-up was a little confined and we can't attain conclusions on lengthy-time period efficacy; in this appreciate, it's also not viable to compare long-term efficacy of autologous PRGD and serum because of the constrained statistics attainable.
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LPI [21 Certification Exam(s) ]
LSI [3 Certification Exam(s) ]
Magento [3 Certification Exam(s) ]
Maintenance [2 Certification Exam(s) ]
McAfee [8 Certification Exam(s) ]
McData [3 Certification Exam(s) ]
Medical [25 Certification Exam(s) ]
Microsoft [354 Certification Exam(s) ]
Mile2 [2 Certification Exam(s) ]
Military [1 Certification Exam(s) ]
Misc [1 Certification Exam(s) ]
Motorola [7 Certification Exam(s) ]
mySQL [4 Certification Exam(s) ]
NCLEX [2 Certification Exam(s) ]
Network-General [12 Certification Exam(s) ]
NetworkAppliance [36 Certification Exam(s) ]
NI [1 Certification Exam(s) ]
Nokia [6 Certification Exam(s) ]
Nortel [130 Certification Exam(s) ]
Novell [37 Certification Exam(s) ]
OMG [10 Certification Exam(s) ]
Oracle [256 Certification Exam(s) ]
P&C [1 Certification Exam(s) ]
Palo-Alto [3 Certification Exam(s) ]
PARCC [1 Certification Exam(s) ]
PayPal [1 Certification Exam(s) ]
Pegasystems [11 Certification Exam(s) ]
PEOPLECERT [4 Certification Exam(s) ]
PMI [15 Certification Exam(s) ]
Polycom [2 Certification Exam(s) ]
PostgreSQL-CE [1 Certification Exam(s) ]
Prince2 [6 Certification Exam(s) ]
PRMIA [1 Certification Exam(s) ]
PsychCorp [1 Certification Exam(s) ]
PTCB [2 Certification Exam(s) ]
QAI [1 Certification Exam(s) ]
QlikView [1 Certification Exam(s) ]
Quality-Assurance [7 Certification Exam(s) ]
RACC [1 Certification Exam(s) ]
Real-Estate [1 Certification Exam(s) ]
RedHat [8 Certification Exam(s) ]
RES [5 Certification Exam(s) ]
Riverbed [8 Certification Exam(s) ]
RSA [15 Certification Exam(s) ]
Sair [8 Certification Exam(s) ]
Salesforce [5 Certification Exam(s) ]
SANS [1 Certification Exam(s) ]
SAP [98 Certification Exam(s) ]
SASInstitute [15 Certification Exam(s) ]
SAT [1 Certification Exam(s) ]
SCO [9 Certification Exam(s) ]
SCP [6 Certification Exam(s) ]
SDI [3 Certification Exam(s) ]
See-Beyond [1 Certification Exam(s) ]
Siemens [1 Certification Exam(s) ]
Snia [7 Certification Exam(s) ]
SOA [15 Certification Exam(s) ]
Social-Work-Board [1 Certification Exam(s) ]
SpringSource [1 Certification Exam(s) ]
SUN [63 Certification Exam(s) ]
SUSE [1 Certification Exam(s) ]
Sybase [17 Certification Exam(s) ]
Symantec [133 Certification Exam(s) ]
Teacher-Certification [3 Certification Exam(s) ]
The-Open-Group [8 Certification Exam(s) ]
TIA [3 Certification Exam(s) ]
Tibco [18 Certification Exam(s) ]
Trend [1 Certification Exam(s) ]
TruSecure [1 Certification Exam(s) ]
USMLE [1 Certification Exam(s) ]
VCE [6 Certification Exam(s) ]
Veeam [2 Certification Exam(s) ]
Veritas [28 Certification Exam(s) ]
Vmware [54 Certification Exam(s) ]
Wonderlic [1 Certification Exam(s) ]
Worldatwork [2 Certification Exam(s) ]
XML-Master [3 Certification Exam(s) ]
Zend [6 Certification Exam(s) ]
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